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DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2014-09-04
  • AnnouncementXML: Submission_2014-09-15_01:21:56.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Ivo Hendriks
  • Title: Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner
  • Description: SUMOylation is a reversible post-translational modification essential for genome stability. Using high-resolution mass spectrometry, we have studied global SUMOylation in mammalian cells and in a site-specific manner, identifying a total of over 4,300 SUMOylation sites in over 1,600 proteins. Moreover, for the first time in excess of 1,000 SUMOylation sites were identified under standard growth conditions. SUMOylation dynamics were quantitatively studied in response to SUMO protease inhibition, proteasome inhibition and heat shock.
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: sumoylated lysine
  • Instrument: Q Exactive

Dataset History

VersionDatetimeStatusChangeLog Entry
02014-06-13 08:53:00ID requested
12014-09-04 03:47:43announced
22014-09-15 01:21:57announcedUpdated publication reference for PubMed record(s): 25218447.

Publication List

  1. Hendriks IA, D'Souza RC, Yang B, Verlaan-de Vries M, Mann M, Vertegaal AC, Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol, 21(10):927-36(2014) [pubmed]

Keyword List

  1. curator keyword: Biological
  2. submitter keyword: SUMO, SUMO2, SUMO-2, QQTGG, Q87R

Contact List

    Alfred C.O. Vertegaal
    • contact affiliation: Department of Molecular Cell Biology, Leiden University Medical Center, The Netherlands
    • contact email: a.c.o.vertegaal@lumc.nl
    • lab head:
    Ivo Hendriks
    • contact affiliation: Leiden University Medical Center
    • contact email: ivo.a.hendriks@gmail.com
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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