PXD010149

PXD010149 is an original dataset announced via ProteomeXchange.

Title	Dataset in support of patients on clinical suspicion of infective endocarditis included in a study searching for novel putative biomarkers
Description	Infective endocarditis (IE) has high mortality, partly due to delayed diagnosis and treatment. Currently, no biomarker can identify IE in patients with fever and clinical picture of infection. To find putative biomarkers we analyzed serum levels of two proteins found in cardiac valves, osteoprotegerin and fibulin-1 among 689 and 696 patients on clinical suspicion of IE, respectively. In addition, proteomic analyses were performed in 24 patients with bacteremia, 12 patients with definite IE and 12 patients with excluded IE.
HostingRepository	PRIDE
AnnounceDate	2020-02-26
AnnouncementXML	Submission_2020-02-26_00:48:48.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Allan Stensballe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-06-18 02:15:54	ID requested
⏵ 1	2020-02-26 00:48:49	announced

Snips, ø, yr MG, Wiggers H, Ludvigsen M, Stensballe A, Vorum H, Poulsen SH, Rasmussen LM, Petersen E, Honor, é B, Towards identification of novel putative biomarkers for infective endocarditis by serum proteomic analysis. Int J Infect Dis, 96():73-81(2020) [pubmed]

curator keyword: Biomedical

submitter keyword: Biomarkers

Infective endocarditis

LFQ LC-MS/MS

Non-infective endocarditis

Serum proteomics

2D-PAGE

Allan Stensballe
contact affiliation	Laboratory for Medical Massspectroemtry Aalborg University
contact email	as@hst.aau.dk
lab head
Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/02/PXD010149

PRIDE project URI

• PRIDE
  1. PXD010149
     1. Label: PRIDE project
     2. Name: Dataset in support of patients on clinical suspicion of infective endocarditis included in a study searching for novel putative biomarkers