PXD050140

PXD050140 is an original dataset announced via ProteomeXchange.

Title	Use of Proteomics for Dietary Reconstruction: a Case Study using Animal Teeth from Ancient Mesopotamia
Description	This research examines animal teeth from Early Dynastic (2900-2350 BC) Mesopotamia (Southern Iraq) to assess animal management practices and identify consumption patterns in animal diets. The objective to answer larger questions about food management and environmental resilience in ancient early complex societies in the Near East was achieved by the use of mass spectrometry-based proteomics for dietary reconstruction. Dietary MS, a revolutionary new methodology applying proteomics techniques to archaeological sample sets to reconstruct ancient animal diet. A developed protein extraction technique followed by liquid chromatography tandem mass spectrometry allowed the identification of the specific plant species consumed in order to highlight variable herd management strategies, resource optimization, for each taxon over time. It also provided information on overall health and indications of disease. This is the first study to apply a full suite of analyses to the region and provides the foundations of a necessary long-term view of human interaction within an environment through both time and space.
HostingRepository	PRIDE
AnnounceDate	2025-03-24
AnnouncementXML	Submission_2025-03-24_04:22:41.132.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Paulos Chumala
SpeciesList	scientific name: environmental samples ; NCBI TaxID: 1092586;
ModificationList	carbamoylated residue; phosphorylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	6550A iFunnel Q-TOF LC/MS

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-26 02:36:56	ID requested
⏵ 1	2025-03-24 04:22:41	announced

Tomilin M, Greenfield T, Chumala P, Katselis GS, Use of Proteomics for Dietary Reconstruction: A Case Study Using Animal Teeth from Ancient Mesopotamia. J Proteome Res, 23(9):4095-4101(2024) [pubmed]

10.1021/acs.jproteome.4c00446;

ProteomeXchange project tag: Skeletal Muscle Proteome (B/D-HPP)

submitter keyword: Ancient Mesopotamia, Dietary Reconstruction, Osteological animal, Animal teeth proteomics

George Katselis
contact affiliation	Department of Medicine, Division of Canadian Centre for Rural and Agricultural Health, College of Medicine, University of Saskatchewan
contact email	george.katselis@usask.ca
lab head
Paulos Chumala
contact affiliation	Canadian Centre for Rural and Agricultural Heatlh , College of Medicine, University of Saskatchewan
contact email	pab776@mail.usask.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD050140

PRIDE project URI

• PRIDE
  1. PXD050140
     1. Label: PRIDE project
     2. Name: Use of Proteomics for Dietary Reconstruction: a Case Study using Animal Teeth from Ancient Mesopotamia