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PXD009420

PXD009420 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA proteome-integrated, carbon source dependent genetic regulatory network in Saccharomyces cerevisiae
DescriptionWe propose a carbon source dependent genetic regulatory network for the budding yeast Saccharomyces cerevisiae, derived from quantitative proteomic analyses integrated with bioinformatics knowledge of regulatory pathways and protein interactions. The proposed network, comprising 1247 transcription factor interactions and 126 chaperone interactions, defines the proteome shift in the cell when growing under different carbon sources. We used a label-free proteomics strategy to quantify alterations in protein abundance for S. cerevisiae when grown on minimal media using glucose, galactose, maltose and trehalose as sole carbon sources.
HostingRepositoryPRIDE
AnnounceDate2021-03-22
AnnouncementXMLSubmission_2021-03-22_10:48:30.625.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterManuel Garcia-Albornoz
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListmonohydroxylated residue; acetylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-04-06 01:47:45ID requested
12021-03-22 10:48:31announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: S. cerevisiae, yeast, proteomics, shotgun proteomics, regulatory network
Contact List
Simon Hubbard
contact affiliationProfessor of Computational Biology Division Head, Evolution and Genomic Sciences School of Biological Sciences | Faculty of Biology, Medicine and Health The University of Manchester, Michael Smith Building, Manchester M13 9PT
contact emailsimon.hubbard@manchester.ac.uk
lab head
Manuel Garcia-Albornoz
contact affiliationUniversity of Manchester
contact emailmanuel.garciaalbornoz@manchester.ac.uk
dataset submitter
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Dataset FTP location
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