PXD009420-2

PXD009420 is an original dataset announced via ProteomeXchange.

Title	A proteome-integrated, carbon source dependent genetic regulatory network in Saccharomyces cerevisiae
Description	We propose a carbon source dependent genetic regulatory network for the budding yeast Saccharomyces cerevisiae, derived from quantitative proteomic analyses integrated with bioinformatics knowledge of regulatory pathways and protein interactions. The proposed network, comprising 1247 transcription factor interactions and 126 chaperone interactions, defines the proteome shift in the cell when growing under different carbon sources. We used a label-free proteomics strategy to quantify alterations in protein abundance for S. cerevisiae when grown on minimal media using glucose, galactose, maltose and trehalose as sole carbon sources.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:20:12.946.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Manuel Garcia-Albornoz
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	acetylated residue; monohydroxylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-06 01:47:45	ID requested
1	2021-03-22 10:48:31	announced
⏵ 2	2024-10-22 05:20:13	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: proteomics, shotgun proteomics, regulatory network, yeast,S. cerevisiae

Simon Hubbard
contact affiliation	Professor of Computational Biology Division Head, Evolution and Genomic Sciences School of Biological Sciences | Faculty of Biology, Medicine and Health The University of Manchester, Michael Smith Building, Manchester M13 9PT
contact email	simon.hubbard@manchester.ac.uk
lab head
Manuel Garcia-Albornoz
contact affiliation	University of Manchester
contact email	manuel.garciaalbornoz@manchester.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD009420

PRIDE project URI

• PRIDE
  1. PXD009420
     1. Label: PRIDE project
     2. Name: A proteome-integrated, carbon source dependent genetic regulatory network in Saccharomyces cerevisiae