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PXD023401 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUnbiased characterization and systematic profiling of metabolically labeled RNA-binding sites
DescriptionHere we introduce pRBS-ID, an amenable platform that enables robust profiling of PAR-crosslinked RBSs. Using tandem mass spectrometry (MS/MS) approaches, we unbiasedly characterize the PAR adducts on peptides, to develop an optimal MS/MS search pipeline that enables robust identification and quantification. Using pRBS-ID, we systematically profile RBSs crosslinked to U or G in PAR-labeled mRNA, which can serve as a rich resource for studying RNA-protein interactions. Especially, pRBS-ID is widely applicable to studies on time-course RNP remodelling, host-virus interactions, and RNP structure prediction.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJong Woo Bae
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-04 04:14:47ID requested
12021-11-02 04:14:57announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, LC-MS/MS
Contact List
Jong-Seo Kim
contact affiliationSchool of Biological Sciences, Seoul National University, Seoul, Korea Center for RNA Research, Institute for Basic Science
contact emailjongseokim@snu.ac.kr
lab head
Jong Woo Bae
contact affiliationSeoul National University
contact emailjakenizer@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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