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PXD030494 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBaseline Proteomics Characterisation of Biomanufacturing Organism Halomonas Bluephagenesis
DescriptionBiomanufacturing remains financially uncompetitive with the lower cost but higher carbon emitting hydrocarbon based chemical industry. Novel chassis organisms may enable cost reductions with respect to traditional chassis such as E. coli and so open an economic rout to low emission biomanufacturing. Extremophile bacteria exemplify that potential. Salt tolerant halomonas species thrive in conditions inimical to other organisms. Their adoption would eliminate the cost of sterilising equipment. Novel chassis are inevitably poorly understood in comparison to established organisms. Rapid characterisation and community data sharing will facilitate organisms’ adoption for biomanufacturing. This paper describes baseline proteomics data set for Halomonas bluephagenesis TD01 under active development for biomanufactoring. The data record comprises a newly sequenced genome for the organism; evidence for expression of 1150 proteins (30% of the proteome) including baseline quantification of 1050 proteins (27% of the proteome) and a spectral library enabling re-use for targeted proteomics assays. Protein data is annotated with KEGG Orthology enabling rapid matching of quantitative data to pathways of interest to biomanufacturing.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMatthew Russell
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Halomonas sp. TD01; NCBI TaxID: 999141;
ModificationListiodoacetamide derivatized residue
InstrumentXevo G2-S QTof
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-12-17 13:21:00ID requested
12022-07-11 08:43:21announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Halomonas, Biomanufacturing, Biotechnology, Spectral Library
Contact List
Nigel Scrutton
contact affiliationFuture Biomanufacturing Research Hub University of Manchester
contact emailnigel.scrutton@manchester.ac.uk
lab head
Matthew Russell
contact affiliationUniversity of Manchester
contact emailrussell.matthew.r@gmail.com
dataset submitter
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Dataset FTP location
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