PXD033668 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Top-Down proteomics and Bottom-Up terminomics for the Detection of Protein Termini in C. elegans |
Description | Here we investigate how top-down proteomics (TDP) can be of value for the detection of protein termini. Either GELFrEE or solid-phase enrichment was conducted for pre-fraction. To verify the detected N-termini HUNTER (High-efficiency Undecanal-based N Termini EnRichment) was employed. Reductive dimethylation on intact protein level was additionally applied. |
HostingRepository | PRIDE |
AnnounceDate | 2022-09-26 |
AnnouncementXML | Submission_2022-09-26_04:23:58.131.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Andreas Tholey |
SpeciesList | scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; |
ModificationList | acetylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-05 00:33:33 | ID requested | |
⏵ 1 | 2022-09-26 04:23:58 | announced | |
2 | 2023-11-14 08:56:23 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: C. Elegans, Orbitrap Fusion Lumos, Orbitrap Q Exactive Plus, ProSight, GELFrEE, Informed Proteomics, MSPathFinder, Top-Down Proteomic, Bottom-Up Proteomics |
Contact List
Andreas Tholey |
contact affiliation | Systematic Proteome Research & Bioanalytics, Institute for Experimental Medicine, Christian-Albrechts-Universität zu Kiel, Kiel, Germany (lab head) |
contact email | a.tholey@iem.uni-kiel.de |
lab head | |
Andreas Tholey |
contact affiliation | Systematic Proteome Research & Bioanalytics, University of Kiel |
contact email | a.tholey@iem.uni-kiel.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/09/PXD033668 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033668
- Label: PRIDE project
- Name: Top-Down proteomics and Bottom-Up terminomics for the Detection of Protein Termini in C. elegans