PXD034890-1

PXD034890 is an original dataset announced via ProteomeXchange.

Title	Prtg+ve Rhombic Lip Ventricular Zone Stem Cells Initiate and Maintain Group 3 Medulloblastoma
Description	PRTG+ve cells show high self renewability in Group 3 medulloblastoma tumors. To access the proteins differentially expressed in this subset of cells, we sorted PRTG+ve and PRTG-ve cells by surface staining with Anti-PRTG antibody from Gr3 medulloblastoma xenografts.
HostingRepository	PRIDE
AnnounceDate	2024-07-31
AnnouncementXML	Submission_2024-07-31_12:51:11.578.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Abhirami Visvanathan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-26 07:21:54	ID requested
⏵ 1	2024-07-31 12:51:12	announced
2	2024-10-22 06:52:00	announced	2024-10-22: Updated project metadata.

10.1016/j.cell.2024.06.011;

Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme W, Delaidelli A, Shin S, Millman J, Bryant A, Abeysundara N, Wu X, Hendrikse LD, Patil V, Bashardanesh Z, Golser J, Livingston BG, Nakashima T, Funakoshi Y, Ong W, Rasnitsyn A, Aldinger KA, Richman CM, Van Ommeren R, Lee JJY, Ly M, Vladoiu MC, Kharas K, Balin P, Erickson AW, Fong V, Zhang J, Su, á, rez RA, Wang H, Huang N, Pallota JG, Douglas T, Haapasalo J, Razavi F, Silvestri E, Sirbu O, Worme S, Kameda-Smith MM, Wu X, Daniels C, MichaelRaj AK, Bhaduri A, Schramek D, Suzuki H, Garzia L, Ahmed N, Kleinman CL, Stein LD, Dirks P, Dunham C, Jabado N, Rich JN, Li W, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Millen KJ, Ellison DW, Dimitrov DS, Taylor MD, stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma. Cell, 187(17):4733-4750.e26(2024) [pubmed]

submitter keyword: Tumor initiating cells, CAR T cell therapy,Medulloblastoma, Group 3, rhombic lip, cell of origin

Dr. Michael D. Taylor
contact affiliation	Neurosurgeon & Senior Scientist Developmental and Stem Cell Biology, The Hospital for Sick Children, Canada
contact email	mdtaylor@sickkids.ca
lab head
Abhirami Visvanathan
contact affiliation	Hospital for Sick children
contact email	abhirami.visvanathan@sickkids.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD034890

PRIDE project URI

• PRIDE
  1. PXD034890
     1. Label: PRIDE project
     2. Name: Prtg+ve Rhombic Lip Ventricular Zone Stem Cells Initiate and Maintain Group 3 Medulloblastoma