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PXD063135-2

PXD063135 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	MEIOB-SCRE interaction is indispensable in meiotic recombination and meiotic crossover formation
Description	MEIOB, a meiosis-specific single-stranded DNA-binding protein, plays a crucial role in both early and late stages of crossover formation during recombination. The data were obtained from adult whole testes of WT mice and MEIOB-HA mice. The tissues were homogenized and subjected to immunoprecipitation (IP) using HA magnetic beads. The HA magnetic beads were then boiled in loading buffer at 95°C for 10 min, and the supernatant was collected for mass spectrometry (MS) analysis. Based on the MEIOB-HA IP MS analysis, five potential MEIOB-interacting proteins were identified, including known partners such as RPA1, SPATA22, and RPA3, as well as synaptonemal complex (SC) proteins SYCP1 and SYCP3.
HostingRepository	iProX
AnnounceDate	2025-04-17
AnnouncementXML	Submission_2025-04-23_00:05:35.382.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haiwei Feng
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-20 22:15:37	ID requested
1	2025-04-20 22:15:54	announced
⏵ 2	2025-04-23 00:05:35	announced	2025-04-23: Update information.

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: meiosis, meiob,Testis

Contact List

Haiwei Feng
contact affiliation	South China Hospital, Medical School, Shenzhen University
contact email	fenghaiwei0212@163.com
lab head
Haiwei Feng
contact affiliation	South China Hospital, Medical School, Shenzhen University
contact email	fenghaiwei0212@163.com
dataset submitter

Full Dataset Link List

iProX dataset URI